Issue 8, 2017, Issue in Progress

Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly(lactic/glycolic acid) nanoparticles

Abstract

Amphiphilic hyperbranched polyglycerols (HbPG) were synthesized by dodecyl and octadecyl alcohols as direct initiators for the ring-opening multibranching polymerization of glycidol. These polymers possess molecular weight dependent surface activity, and are efficient surfactants and stabilizers for poly(lactic/glycolic acid) (PLGA) nanoparticles, opening new possibilities for functionalized drug carriers, targeting, imaging agents, etc.

Graphical abstract: Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly(lactic/glycolic acid) nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
06 Dec 2016
Accepted
27 Dec 2016
First published
28 Dec 2016
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 4348-4352

Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly(lactic/glycolic acid) nanoparticles

G. Kasza, G. Gyulai, Á. Ábrahám, G. Szarka, B. Iván and É. Kiss, RSC Adv., 2017, 7, 4348 DOI: 10.1039/C6RA27843D

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