Issue 12, 2017

New advances on the marrying of UCNPs and photothermal agents for imaging-guided diagnosis and the therapy of tumors

Abstract

In recent years, near-infrared (NIR) light, as a powerful means of external stimulus, has attracted widespread attention in the field of tumor research. On one hand, NIR light-excited rare earth upconversion nanoparticles (UCNPs) have presented unique features in multimodal bioimaging, energy conversion and photocontrolled drug delivery. On the other hand, NIR-light-triggered photothermal therapy (PTT) is a minimally invasive approach in the fight against tumors, owing to its high spatial resolution, economic viability and improved target selectivity. Thus, the marrying of UCNPs and NIR photothermal agents could open new avenues in the construction of theranostic nanoplatforms. This review primarily focuses on the new advances in the design and the therapeutic applications of multifunctional UCNPs–NIR absorber nanoplatforms. The future challenges and prospects in this field are also addressed.

Graphical abstract: New advances on the marrying of UCNPs and photothermal agents for imaging-guided diagnosis and the therapy of tumors

Article information

Article type
Review Article
Submitted
30 Nov 2016
Accepted
06 Feb 2017
First published
06 Feb 2017

J. Mater. Chem. B, 2017,5, 2209-2230

New advances on the marrying of UCNPs and photothermal agents for imaging-guided diagnosis and the therapy of tumors

D. Wang, B. Liu, Z. Quan, C. Li, Z. Hou, B. Xing and J. Lin, J. Mater. Chem. B, 2017, 5, 2209 DOI: 10.1039/C6TB03117J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements