Issue 6, 2017

All-in-one thermometer-heater up-converting platform YF3:Yb3+,Tm3+ operating in the first biological window

Abstract

Achieving the combination of real-time diagnosis and therapy in one up-converting platform with sensitive thermometry and efficient heat production is a critical step towards photo-thermal therapy (PTT). Here, the potentiality of truncated octahedral YF3:Tm3+/Yb3+ micro-crystals as thermometers operating in the first biological window (BW-I) was evaluated on the basis of a thermo-responsive fluorescence intensity ratio (FIR) of far-red to NIR emission from completely separated 3F2,3/3H43H6 transitions. The probabilities of cross-relaxation (CR) processes related to 3F2,3/3H4 levels were greatly enhanced by increasing the Yb3+ content, leading to an increase of more than three times in the absolute sensitivity within the physiological temperature range. Photo-thermal effects were also assessed by monitoring the variation of temperature around the samples as functions of the Yb3+ dosage, excitation time and density of 980 nm laser diodes. These results offer a promising strategy to optimize the thermal sensitivity and optical heating ability, which indicates that the present UC platform has great potential applications in PTT as real-time thermometers and photo-thermal agents.

Graphical abstract: All-in-one thermometer-heater up-converting platform YF3:Yb3+,Tm3+ operating in the first biological window

Supplementary files

Article information

Article type
Paper
Submitted
17 Dec 2016
Accepted
04 Jan 2017
First published
05 Jan 2017

J. Mater. Chem. C, 2017,5, 1501-1507

All-in-one thermometer-heater up-converting platform YF3:Yb3+,Tm3+ operating in the first biological window

H. Suo, F. Hu, X. Zhao, Z. Zhang, T. Li, C. Duan, M. Yin and C. Guo, J. Mater. Chem. C, 2017, 5, 1501 DOI: 10.1039/C6TC05449H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements