Issue 12, 2017
From the journal:

Chemical Communications

Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent†

Li-Jing Wang, ORCID logo *a   Manman Chen,a   Lin Qi,a   Zhidong Xua  and  Wei Li*a  

* Corresponding authors

a Key Laboratory of Medicinal Chemistry, and Molecular Diagnosis of the Ministry of Education, College of Chemistry & Environmental Science, HeBei University, 180 Wusi Donglu, Baoding 071002, P. R. China
E-mail: wanglj0405@163.com, liweihebeilab@163.com

Abstract

A novel and efficient Cu(OAc)2-mediated oxysulfonylation of alkenyl oximes with sodium sulfonates was developed. The reactions are easy to conduct, occur under mild conditions, and form a broad range of sulfone-substituted isoxazolines in good yields.

Graphical abstract: Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent

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Article information

DOI
https://doi.org/10.1039/C7CC00090A
Article type
Communication
Submitted
05 Jan 2017
Accepted
23 Jan 2017
First published
24 Jan 2017

Chem. Commun., 2017,53, 2056-2059

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Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent

L. Wang, M. Chen, L. Qi, Z. Xu and W. Li, Chem. Commun., 2017, 53, 2056 DOI: 10.1039/C7CC00090A

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