Issue 27, 2017

SF5-Pyridylaryl-λ3-iodonium salts and their utility as electrophilic reagents to access SF5-pyridine derivatives in the late-stage of synthesis

Abstract

Electrophilic pentafluorosulfanyl (SF5) heteroarylation of target molecules using novel reagents is described. Unsymmetrical diaryliodonium reagents 1 having 2-SF5-pyridine have been synthesized in good yields. They are efficient electrophilic reagents for carbon and heterocentered nucleophiles, producing the corresponding SF5-pyridine derivatives in good to excellent yields.

Graphical abstract: SF5-Pyridylaryl-λ3-iodonium salts and their utility as electrophilic reagents to access SF5-pyridine derivatives in the late-stage of synthesis

Supplementary files

Article information

Article type
Communication
Submitted
09 Feb 2017
Accepted
08 Mar 2017
First published
09 Mar 2017

Chem. Commun., 2017,53, 3850-3853

SF5-Pyridylaryl-λ3-iodonium salts and their utility as electrophilic reagents to access SF5-pyridine derivatives in the late-stage of synthesis

P. Das, M. Takada, K. Matsuzaki, N. Saito and N. Shibata, Chem. Commun., 2017, 53, 3850 DOI: 10.1039/C7CC01043E

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