Issue 33, 2017

Multi-functional, thiophenol-based surface chemistry for surface-enhanced Raman spectroscopy

Abstract

Surface-enhanced Raman spectroscopy (SERS) has been recognized as one of the most sensitive sensing technologies and has been used for a variety of chemical, biological and medical applications. Compared to traditional direct SERS detection using a bare metal SERS-active substrate, surface chemistries and surface modifications on SERS-active substrates are becoming more and more important to achieve the detection of target analytes with a small surface affinity or weak Raman activity. As one special class of surface chemistries and modifications for SERS-active substrates, the thiophenol-based molecules offer new functions, increased sensitivity, and improved specificity to SERS-based sensing. The thiol group helps to form a stable modification on the gold or silver surface of SERS-active substrates, the benzene ring is used to report and amplify the detection signal, and the specific functional group on each thiophenol-based molecule contributes to the detection specificity. This article highlights the recent advances in thiophenol-based surface chemistry for SERS applications. The use of thiophenol-based molecule modified SERS-active substrates for fundamental studies, surface catalysis investigations and chemical and biological sensing is comprehensively discussed.

Graphical abstract: Multi-functional, thiophenol-based surface chemistry for surface-enhanced Raman spectroscopy

Article information

Article type
Feature Article
Submitted
01 Mar 2017
Accepted
23 Mar 2017
First published
28 Mar 2017

Chem. Commun., 2017,53, 4550-4561

Multi-functional, thiophenol-based surface chemistry for surface-enhanced Raman spectroscopy

F. Sun, D. D. Galvan, P. Jain and Q. Yu, Chem. Commun., 2017, 53, 4550 DOI: 10.1039/C7CC01577A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements