Issue 36, 2017

A highly efficient Cu catalyst system for the radical reactions of α-bromocarbonyls

Abstract

In this communication, we established highly efficient Cu-catalyzed ARGET-ATRS (atom-transfer radical substitution) of alpha-bromocarbonyls with styrenes to produce tert-alkylated styrenes. The maximum TON was up to 12 000. Hünig's base was very important to regenerate active CuI. Moreover, a Cu-catalyzed C–C cleavage reaction via SH2′ and intermolecular C–H cyclization of α-bromoimide was found.

Graphical abstract: A highly efficient Cu catalyst system for the radical reactions of α-bromocarbonyls

Supplementary files

Article information

Article type
Communication
Submitted
09 Mar 2017
Accepted
13 Apr 2017
First published
13 Apr 2017

Chem. Commun., 2017,53, 5017-5019

A highly efficient Cu catalyst system for the radical reactions of α-bromocarbonyls

Y. Noda and T. Nishikata, Chem. Commun., 2017, 53, 5017 DOI: 10.1039/C7CC01790A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements