Phage capsid protein-directed MnO2 nanosheets with peroxidase-like activity for spectrometric biosensing and evaluation of antioxidant behaviour

Lei Han; Pei Liu; Haijiao Zhang; Feng Li; Aihua Liu

doi:10.1039/C7CC02049J

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Phage capsid protein-directed MnO₂ nanosheets with peroxidase-like activity for spectrometric biosensing and evaluation of antioxidant behaviour†

Lei Han,

^ab Pei Liu,^bc Haijiao Zhang,^a Feng Li

*^a and Aihua Liu*^cd

Author affiliations

* Corresponding authors

^a College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, 700 Changcheng Road, Qingdao, Shandong, China
E-mail: lifeng@qust.edu.cn

^b University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing, China

^c Institute for Biosensing, and College of Chemistry and Chemical Engineering, and Joint Key Laboratory for Biosensors of Shandong Province, Qingdao University, 308 Ningxia Road, Qingdao, China
E-mail: liuah@qdu.edu.cn

^d College of Medicine, Qingdao University, 38 Dengzhou Road, Qingdao, China

Abstract

Small molecular weight proteins (5.21 kDa) were used as bio-templates to synthesize MnO₂ nanosheets (NSs). This work will open up a protein-directed avenue to synthesize 2D morphology. Further, the as-prepared MnO₂ NSs showed intrinsic peroxidase-like activity and were then applied for glucose detection and evaluation of antioxidant behaviours of typical antioxidants.

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Article information

DOI: https://doi.org/10.1039/C7CC02049J
Article type: Communication
Submitted: 17 Mar 2017
Accepted: 18 Apr 2017
First published: 18 Apr 2017

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Chem. Commun., 2017,53, 5216-5219

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Phage capsid protein-directed MnO₂ nanosheets with peroxidase-like activity for spectrometric biosensing and evaluation of antioxidant behaviour

L. Han, P. Liu, H. Zhang, F. Li and A. Liu, Chem. Commun., 2017, 53, 5216 DOI: 10.1039/C7CC02049J

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Chemical Communications