Issue 90, 2017

Exonuclease-assisted target recycling amplification for label-free chemiluminescence assay and molecular logic operations

Abstract

A versatile exonuclease III (Exo III)-assisted target recycling amplification (Exo-TRA) strategy is demonstrated to achieve label-free and homogeneous chemiluminescence (CL) detection of target DNA. Inspired by this principle, a series of logic gates are constructed using DNA molecules as “inputs” to activate the Exo-TRA system.

Graphical abstract: Exonuclease-assisted target recycling amplification for label-free chemiluminescence assay and molecular logic operations

Supplementary files

Article information

Article type
Communication
Submitted
31 Aug 2017
Accepted
19 Oct 2017
First published
19 Oct 2017

Chem. Commun., 2017,53, 12201-12204

Exonuclease-assisted target recycling amplification for label-free chemiluminescence assay and molecular logic operations

Y. Yan, S. Yue, T. Zhao, B. Luo and S. Bi, Chem. Commun., 2017, 53, 12201 DOI: 10.1039/C7CC06835B

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