Issue 94, 2017

Transition metal-free N-fluoroalkylation of amines using cyanurate activated fluoroalcohols

Abstract

A novel and highly efficient method for N-fluoroalkylation of amines using 2,4,6-tris(fluoroalkoxy)-1,3,5-triazines was developed. This simple approach allowed the N-fluoroalkylation of amines under fast, mild and efficient reaction conditions, without using a transition metal as a catalyst.

Graphical abstract: Transition metal-free N-fluoroalkylation of amines using cyanurate activated fluoroalcohols

Supplementary files

Article information

Article type
Communication
Submitted
23 Sep 2017
Accepted
06 Nov 2017
First published
06 Nov 2017

Chem. Commun., 2017,53, 12650-12653

Transition metal-free N-fluoroalkylation of amines using cyanurate activated fluoroalcohols

F. Haghighi, F. Panahi, M. Golbon Haghighi and A. Khalafi-Nezhad, Chem. Commun., 2017, 53, 12650 DOI: 10.1039/C7CC07428J

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