Issue 15, 2018

Molecularly imprinted polymers as receptor mimics for selective cell recognition

Abstract

Molecularly imprinted polymers (MIPs) have now earned the reputation as “artificial receptors” or “plastic antibodies”. As the mimics of natural receptors, MIPs are reminiscent of some basic functions of natural receptors in living systems, e.g., the ability to interact with or recognize cells. The latest decade has witnessed a great advance in MIPs from simple molecular extraction to efficient cell recognition, implying that MIP-based synthetic receptors are approaching to be perfectly functioning replicates of their natural counterparts. With the most emerging development in molecular imprinting, MIP-mediated cell recognition has now shown great promise in cell biology research, theranostics and regenerative medicine. This tutorial review provides a panoramic view of current MIPs for both microorganism and mammalian cell recognition. The most representative developments of MIP-mediated cell recognition, from initial imprinting strategies to eventual bio-related applications, are highlighted.

Graphical abstract: Molecularly imprinted polymers as receptor mimics for selective cell recognition

Article information

Article type
Tutorial Review
Submitted
09 Feb 2018
First published
07 Jun 2018

Chem. Soc. Rev., 2018,47, 5574-5587

Molecularly imprinted polymers as receptor mimics for selective cell recognition

J. Pan, W. Chen, Y. Ma and G. Pan, Chem. Soc. Rev., 2018, 47, 5574 DOI: 10.1039/C7CS00854F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements