Issue 13, 2018

Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

Abstract

Polymeric nanorods loaded with AIEgens are synthesized via nano-precipitation under ultrasound sonication, where prolonged sonication time could induce a nanodot-to-nanorod transition. These AIE nanorods, but not the nanodots, could be selectively internalized into cancer cells, which show better tumor accumulation, higher tumor penetration and more efficient in vivo cancer cell uptake.

Graphical abstract: Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

Supplementary files

Article information

Article type
Communication
Submitted
11 Dec 2017
Accepted
01 Mar 2018
First published
09 Mar 2018

Nanoscale, 2018,10, 5869-5874

Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

G. Feng, D. Mao, J. Liu, C. C. Goh, L. G. Ng, D. Kong, B. Z. Tang and B. Liu, Nanoscale, 2018, 10, 5869 DOI: 10.1039/C7NR09196F

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