Issue 13, 2018

Secondary structures of synthetic polypeptide polymers

Abstract

Synthetic peptide-based polymers represent a unique class of macromolecules able to mimic the properties of natural proteins in materials sciences since (1) they present the same macromolecular backbone as do proteins, (2) they can be obtained in large scale and in only one step by using the ROP (Ring-Opening Polymerization) methodology, and (3) they can fold into different secondary structures in the same way as do proteins. The control of this structuring ability paves the way to a wide range of applications in materials science, for which uses of natural proteins remain limited. In this review article, the fundamental principles of polypeptide polymer structuring are summarized. It is also highlighted here, how tuning the polypeptide secondary structure could be a key step to modulate various properties in advanced materials (size, rigidity, self-assembly, etc.).

Graphical abstract: Secondary structures of synthetic polypeptide polymers

Article information

Article type
Review Article
Submitted
11 Oct 2017
Accepted
09 Nov 2017
First published
14 Nov 2017

Polym. Chem., 2018,9, 1517-1529

Secondary structures of synthetic polypeptide polymers

C. Bonduelle, Polym. Chem., 2018, 9, 1517 DOI: 10.1039/C7PY01725A

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