Issue 78, 2017
From the journal:

RSC Advances

Fused multifunctionalized isoindole-1,3-diones via the coupled oxidation of imidazoles and tetraynes†

Qiong Hu,‡a   Lidong Li,‡a   Fei Yin,a   Hao Zhang,a   Yadong Hu,a   Baohua Liua  and  Yimin Hu ORCID logo *a  

* Corresponding authors

a Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Key Laboratory of Molecular-Based Materials, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, China
E-mail: yiminhu@ahnu.edu.cn

Abstract

The facile synthesis of fused multifunctionalized isoindole-1,3-diones by a hexadehydro-Diels–Alder domino reaction of various substituted tetraynes and imidazole derivatives is reported. The overall transformation involved the formation of three new C–C bonds and two new Caryl–O bonds via intramolecular cyclization and intermolecular coupling oxidation reactions.

Graphical abstract: Fused multifunctionalized isoindole-1,3-diones via the coupled oxidation of imidazoles and tetraynes

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Article information

DOI
https://doi.org/10.1039/C7RA08817E
Article type
Paper
Submitted
09 Aug 2017
Accepted
13 Oct 2017
First published
25 Oct 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 49810-49816

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Fused multifunctionalized isoindole-1,3-diones via the coupled oxidation of imidazoles and tetraynes

Q. Hu, L. Li, F. Yin, H. Zhang, Y. Hu, B. Liu and Y. Hu, RSC Adv., 2017, 7, 49810 DOI: 10.1039/C7RA08817E

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