Issue 81, 2017

Cobalt(ii)-catalyzed remote C5-selective C–H sulfonylation of quinolines via insertion of sulfur dioxide

Abstract

A novel and simple method for C–H sulfonylation of quinolines based on an inexpensive cobalt catalyst via insertion of sulfur dioxide is established. Excellent selectivity in the C5-position of quinolines is observed. This transformation has no need of oxidant and additive, affording sulfonated products in moderate to good yields. Furthermore, aromatic amines can displace aryldiazonium tetrafluoroborates as original materials via the in situ diazotization. The results of control experiments indicate that a radical pathway is involved in this sulfonylation.

Graphical abstract: Cobalt(ii)-catalyzed remote C5-selective C–H sulfonylation of quinolines via insertion of sulfur dioxide

Supplementary files

Article information

Article type
Paper
Submitted
15 Oct 2017
Accepted
30 Oct 2017
First published
03 Nov 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 51313-51317

Cobalt(II)-catalyzed remote C5-selective C–H sulfonylation of quinolines via insertion of sulfur dioxide

K. Wang, G. Wang, G. Duan and C. Xia, RSC Adv., 2017, 7, 51313 DOI: 10.1039/C7RA11363C

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