Issue 4, 2018

Enantioselective cellular localisation of europium(iii) coordination complexes

Abstract

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.

Graphical abstract: Enantioselective cellular localisation of europium(iii) coordination complexes

Supplementary files

Article information

Article type
Edge Article
Submitted
12 Oct 2017
Accepted
06 Dec 2017
First published
06 Dec 2017
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2018,9, 1042-1049

Enantioselective cellular localisation of europium(III) coordination complexes

A. T. Frawley, Holly V. Linford, M. Starck, R. Pal and D. Parker, Chem. Sci., 2018, 9, 1042 DOI: 10.1039/C7SC04422D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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