Issue 15, 2018
From the journal:

Analyst

A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT-activated FRET mechanism and its bioimaging application in living cells and zebrafish†

Kaixin Xu,a   Longwei He, ORCID logo a   Xueling Yang,a   Yunzhen Yanga  and  Weiying Lin ORCID logo *a  

* Corresponding authors

a Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China
E-mail: weiyinglin2013@163.com

Abstract

A H2O2-responsive fluorescent chemosensor (CNBE) with a ratiometric emission signal was elaborately designed and synthesized. The ratio signal of the chemosensor was manipulated by an interplaying ICT-activated FRET mechanism. The ratiometric fluorescence imaging was successfully applied to detect H2O2 using CNBE in living cells and zebrafish.

Graphical abstract: A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT-activated FRET mechanism and its bioimaging application in living cells and zebrafish

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Article information

DOI
https://doi.org/10.1039/C8AN00842F
Article type
Communication
Submitted
06 May 2018
Accepted
20 Jun 2018
First published
28 Jun 2018

Analyst, 2018,143, 3555-3559

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A ratiometric fluorescent hydrogen peroxide chemosensor manipulated by an ICT-activated FRET mechanism and its bioimaging application in living cells and zebrafish

K. Xu, L. He, X. Yang, Y. Yang and W. Lin, Analyst, 2018, 143, 3555 DOI: 10.1039/C8AN00842F

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