Issue 48, 2018

Boronic acid liposomes for cellular delivery and content release driven by carbohydrate binding

Abstract

Boronic acid liposomes enable triggered content release and cell delivery driven by carbohydrate binding. Dye release assays using hydrophilic and hydrophobic fluorophores validate dose-dependent release upon carbohydrate treatment. Microscopy results indicate dramatic enhancements in cell delivery, showcasing the prospects of boronic acid lipids for drug delivery.

Graphical abstract: Boronic acid liposomes for cellular delivery and content release driven by carbohydrate binding

Supplementary files

Article information

Article type
Communication
Submitted
30 Jan 2018
Accepted
19 May 2018
First published
21 May 2018

Chem. Commun., 2018,54, 6169-6172

Author version available

Boronic acid liposomes for cellular delivery and content release driven by carbohydrate binding

X. Zhang, D. S. Alves, J. Lou, S. D. Hill, F. N. Barrera and M. D. Best, Chem. Commun., 2018, 54, 6169 DOI: 10.1039/C8CC00820E

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