Issue 22, 2018
From the journal:

Chemical Communications

Palladium-catalyzed site-selective arylation of aliphatic ketones enabled by a transient ligand†

Lei Pan, ORCID logo ‡a   Ke Yang,‡ab   Guigen Li ORCID logo *bc  and  Haibo Ge ORCID logo *a  

* Corresponding authors

a Department of Chemistry and Chemical Biology, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA
E-mail: Ge-geh@iupui.edu

b Institute of Chemistry & BioMedical Sciences, Nanjing University, Nanjing 210093, P. R. China

c Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA
E-mail: Li-guigen.li@ttu.edu

Abstract

Transition metal-catalyzed direct C–H bond functionalization enabled by transient ligands has become an attractive topic. Here we report a palladium-catalyzed site-selective arylation of β-C(sp3)–H bonds in aliphatic ketones with β-alanine as the transient ligand.

Graphical abstract: Palladium-catalyzed site-selective arylation of aliphatic ketones enabled by a transient ligand

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8CC00980E
Article type
Communication
Submitted
04 Feb 2018
Accepted
16 Feb 2018
First published
16 Feb 2018

Chem. Commun., 2018,54, 2759-2762

Permissions

Request permissions

Palladium-catalyzed site-selective arylation of aliphatic ketones enabled by a transient ligand

L. Pan, K. Yang, G. Li and H. Ge, Chem. Commun., 2018, 54, 2759 DOI: 10.1039/C8CC00980E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements