Issue 56, 2018

A DNA–linker–DNA bifunctional probe for simultaneous SERS detection of miRNAs via symmetric signal amplification

Abstract

In this work, using a dual functional DNA–linker–DNA (DLD) probe, a new concept of a symmetric signal amplification (SSA) reaction is introduced to simultaneously analyze miRNAs. By coupling the surface-enhanced Raman scattering (SERS) technology with symmetric amplification modes, this flexible biosensing system exhibits high sensitivity and specificity.

Graphical abstract: A DNA–linker–DNA bifunctional probe for simultaneous SERS detection of miRNAs via symmetric signal amplification

Supplementary files

Article information

Article type
Communication
Submitted
12 Apr 2018
Accepted
14 Jun 2018
First published
16 Jun 2018

Chem. Commun., 2018,54, 7786-7789

A DNA–linker–DNA bifunctional probe for simultaneous SERS detection of miRNAs via symmetric signal amplification

S. Ye, M. Wang, Z. Wang, N. Zhang and X. Luo, Chem. Commun., 2018, 54, 7786 DOI: 10.1039/C8CC02910E

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