Issue 69, 2018

Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry

Abstract

A signal amplification protocol based on mass spectrometry (MS) was developed to profile simultaneously multiple biomarkers from a single cell using various mass label (ML)-modified Au nanoparticles (AuNPs). The strategy with ultrahigh sensitivity and specificity has potential prospects in the deep exploration of molecular and cellular characterization.

Graphical abstract: Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry

Supplementary files

Article information

Article type
Communication
Submitted
02 Jul 2018
Accepted
06 Aug 2018
First published
06 Aug 2018

Chem. Commun., 2018,54, 9659-9662

Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry

Y. Wang, R. Du, L. Qiao and B. Liu, Chem. Commun., 2018, 54, 9659 DOI: 10.1039/C8CC05308A

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