Issue 12, 2019

An integrated platform for the capture of circulating tumor cells and in situ SERS profiling of membrane proteins through rational spatial organization of multi-functional cyclic RGD nanopatterns

Abstract

It is significant to in situ monitor membrane proteins at the single-cell level for understanding the cell function. Herein, an integrated platform was designed and constructed for highly efficient cell capture and in situ sensitive SERS determination of HER2 activity in cells through rational spatial organization of multi-functional cyclic RGD nanopatterns at a disordered mesoporous gold film via electrochemical activation.

Graphical abstract: An integrated platform for the capture of circulating tumor cells and in situ SERS profiling of membrane proteins through rational spatial organization of multi-functional cyclic RGD nanopatterns

Supplementary files

Article information

Article type
Communication
Submitted
16 Nov 2018
Accepted
08 Jan 2019
First published
08 Jan 2019

Chem. Commun., 2019,55, 1730-1733

An integrated platform for the capture of circulating tumor cells and in situ SERS profiling of membrane proteins through rational spatial organization of multi-functional cyclic RGD nanopatterns

H. Dong, D. Yao, Q. Zhou, L. Zhang and Y. Tian, Chem. Commun., 2019, 55, 1730 DOI: 10.1039/C8CC09108K

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