Issue 17, 2018

Transition-metal-free photoredox intermolecular α-arylation of ketones

Abstract

α-Arylation of ketones with electron rich arenes via sp2(C)–H has been achieved by the reaction of α-phenylselanylketones using organic photoredox catalysis. The reaction proceeds via an α-methylene ketone radical generated by sp3(C)–SePh activation. The developed method has been found to have broad substrate scope and is free from the use of pre-functionalized aromatics.

Graphical abstract: Transition-metal-free photoredox intermolecular α-arylation of ketones

Supplementary files

Article information

Article type
Research Article
Submitted
24 May 2018
Accepted
31 Jul 2018
First published
03 Aug 2018

Org. Chem. Front., 2018,5, 2610-2614

Transition-metal-free photoredox intermolecular α-arylation of ketones

G. Pandey, S. K. Tiwari, A. Budakoti and P. K. Sahani, Org. Chem. Front., 2018, 5, 2610 DOI: 10.1039/C8QO00510A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements