Issue 22, 2018, Issue in Progress

Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

Abstract

A simple and efficient metal-free arylation of imidazo[1,2-a]pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology demonstrates the usefulness of commercially available aryl hydrazine as an arylating agent.

Graphical abstract: Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

Supplementary files

Article information

Article type
Paper
Submitted
16 Feb 2018
Accepted
19 Mar 2018
First published
03 Apr 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 12360-12367

Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

S. Jana, S. Samanta, A. K. Bagdi, V. Z. Shirinian and A. Hajra, RSC Adv., 2018, 8, 12360 DOI: 10.1039/C8RA01474D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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