A near-infrared emission fluorescent probe with multi-rotatable moieties for highly sensitive detection of mitochondrial viscosity in an inflammatory cell model

Yanyan Ma; Yuping Zhao; Rui Guo; Linlin Zhu; Weiying Lin

doi:10.1039/C8TB02083C

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A near-infrared emission fluorescent probe with multi-rotatable moieties for highly sensitive detection of mitochondrial viscosity in an inflammatory cell model†

Yanyan Ma,

^a Yuping Zhao,^a Rui Guo,

^b Linlin Zhu^a and Weiying Lin

*^a

Author affiliations

* Corresponding authors

^a Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China
E-mail: weiyinglin2013@163.com

^b State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China

Abstract

A near-infrared emission fluorescent viscosity probe (TPE-V) which contains multi-rotatable moieties has been developed for the first time. TPE-V exhibited a large Stokes shift (190 nm) and a large enhancement in fluorescence intensity (100-fold) in response to viscosity. Moreover, TPE-V was successfully applied for the detection of mitochondrial viscosity in an inflammatory cell model.

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Article information

DOI: https://doi.org/10.1039/C8TB02083C
Article type: Communication
Submitted: 08 Aug 2018
Accepted: 04 Sep 2018
First published: 04 Sep 2018

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J. Mater. Chem. B, 2018,6, 6212-6216

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A near-infrared emission fluorescent probe with multi-rotatable moieties for highly sensitive detection of mitochondrial viscosity in an inflammatory cell model

Y. Ma, Y. Zhao, R. Guo, L. Zhu and W. Lin, J. Mater. Chem. B, 2018, 6, 6212 DOI: 10.1039/C8TB02083C

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Journal of Materials Chemistry B

A near-infrared emission fluorescent probe with multi-rotatable moieties for highly sensitive detection of mitochondrial viscosity in an inflammatory cell model†

Abstract

Supplementary files

Article information

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A near-infrared emission fluorescent probe with multi-rotatable moieties for highly sensitive detection of mitochondrial viscosity in an inflammatory cell model

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