Issue 50, 2019

An indicator displacement assay recognizes enantiomers of chiral carboxylates

Abstract

Two chiral copper(II)-based receptors—[CuRRL]2+ and [CuSSL]2+—in conjuction with the fluorescent indicator coumarin 343 were used to establish an enantioselective indicator displacement assay (eIDA) for the determination of the enantiomeric composition of chiral carboxylates such as ibuprofen, naproxen and atorvastatin.

Graphical abstract: An indicator displacement assay recognizes enantiomers of chiral carboxylates

Supplementary files

Article information

Article type
Communication
Submitted
30 Apr 2019
Accepted
27 May 2019
First published
28 May 2019

Chem. Commun., 2019,55, 7183-7186

An indicator displacement assay recognizes enantiomers of chiral carboxylates

S. Sheykhi, L. Mosca, J. M. Durgala and P. Anzenbacher, Chem. Commun., 2019, 55, 7183 DOI: 10.1039/C9CC03352A

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