In this work, a unique dual-site controlled fluorescent probe was presented for the sensitive and concurrent detection of pH in the cytoplasm and lysosomes. With the probe, the simultaneous down-regulation of pH in the lysosomes and cytoplasm during autophagy has been successfully revealed for the first time.
M. Tian, C. Liu, B. Dong, Y. Zuo and W. Lin, Chem. Commun., 2019, 55, 10440 DOI: 10.1039/C9CC03679B
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