Issue 75, 2019
From the journal:

Chemical Communications

The stepwise photodamage of organelles by two-photon luminescent ruthenium(ii) photosensitizers†

Kangqiang Qiu,‡ab   Ya Wen,‡b   Cheng Ouyang,b   Xinxing Liao,b   Chaofeng Liu,b   Thomas W. Rees,b   Qianling Zhang, ORCID logo *a   Liangnian Jib  and  Hui Chao ORCID logo *ab  

* Corresponding authors

a College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, P. R. China
E-mail: zhql@szu.edu.cn

b MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou 510275, P. R. China
E-mail: ceschh@mail.sysu.edu.cn

Abstract

Ru(II) polypyridyl complexes, containing a morpholine moiety, and possessing two-photon absorption properties and pH dependent singlet oxygen production were used for stepwise lysosomes-to-mitochondria photodamage of cancer cells.

Graphical abstract: The stepwise photodamage of organelles by two-photon luminescent ruthenium(ii) photosensitizers

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Article information

DOI
https://doi.org/10.1039/C9CC05962H
Article type
Communication
Submitted
31 Jul 2019
Accepted
27 Aug 2019
First published
27 Aug 2019

Chem. Commun., 2019,55, 11235-11238

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The stepwise photodamage of organelles by two-photon luminescent ruthenium(II) photosensitizers

K. Qiu, Y. Wen, C. Ouyang, X. Liao, C. Liu, T. W. Rees, Q. Zhang, L. Ji and H. Chao, Chem. Commun., 2019, 55, 11235 DOI: 10.1039/C9CC05962H

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