Issue 79, 2019

Regioselective radical hydroboration of electron-deficient alkenes: synthesis of α-boryl functionalized molecules

Abstract

A regioselective radical hydroboration of various electron-deficient alkenes is achieved by the employment of an NHC–boryl radical. A range of α-borylated nitriles, trifluoromethyl molecules, phosphonates, sulfones, and gem-diboron compounds have been prepared from readily available starting materials. Further synthetic applications of these products are also demonstrated.

Graphical abstract: Regioselective radical hydroboration of electron-deficient alkenes: synthesis of α-boryl functionalized molecules

Supplementary files

Article information

Article type
Communication
Submitted
22 Aug 2019
Accepted
05 Sep 2019
First published
06 Sep 2019

Chem. Commun., 2019,55, 11904-11907

Regioselective radical hydroboration of electron-deficient alkenes: synthesis of α-boryl functionalized molecules

Y. Huang, J. Wang, W. Zheng, F. Zhang, Y. Yu, M. Zheng, X. Zhou and Y. Wang, Chem. Commun., 2019, 55, 11904 DOI: 10.1039/C9CC06506G

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