Iron phosphide nanoparticles as a pH-responsive T1 contrast agent for magnetic resonance tumor imaging

Yuan Qiu; Weiwen Lin; Lili Wang; Rui Liu; Jiangao Xie; Xin Chen; Feifei Yang; Guoming Huang; Huanghao Yang

doi:10.1039/C9RA06886D

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Iron phosphide nanoparticles as a pH-responsive T₁ contrast agent for magnetic resonance tumor imaging†

Yuan Qiu,‡^a Weiwen Lin,‡^b Lili Wang,‡^b Rui Liu,^a Jiangao Xie,^b Xin Chen,^a Feifei Yang,^a Guoming Huang

*^a and Huanghao Yang

*^c

Author affiliations

* Corresponding authors

^a College of Biological Science and Engineering, Fuzhou University, Fuzhou 350116, P. R. China
E-mail: gmhuang@fzu.edu.cn

^b Department of Diagnostic Radiology, Union Hospital, Fujian Medical University, Fuzhou 350001, P. R. China

^c MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou 350116, P. R. China
E-mail: hhyang@fzu.edu.cn

Abstract

In this work, the potential of FeP nanoparticles as a pH-responsive T₁ contrast agent was investigated. The FeP nanoparticles have good biocompatibility and can significantly amplify T₁ magnetic resonance signals in response to the acidic microenvironment of solid tumors, holding great promise in serving as an acid-activatable T₁ contrast agent for tumor imaging.

Download options Please wait...

Supplementary files

Supplementary information PDF (1070K)

Article information

DOI: https://doi.org/10.1039/C9RA06886D
Article type: Paper
Submitted: 30 Aug 2019
Accepted: 17 Sep 2019
First published: 26 Sep 2019
This article is Open Access

Download Citation

RSC Adv., 2019,9, 30581-30584

Permissions

Request permissions

Iron phosphide nanoparticles as a pH-responsive T₁ contrast agent for magnetic resonance tumor imaging

Y. Qiu, W. Lin, L. Wang, R. Liu, J. Xie, X. Chen, F. Yang, G. Huang and H. Yang, RSC Adv., 2019, 9, 30581 DOI: 10.1039/C9RA06886D

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

RSC Advances