Issue 44, 2019

Robust organic nanoparticles for noninvasive long-term fluorescence imaging

Abstract

Fluorescence imaging is a non-invasive imaging technique, which facilitates the visualization of sub-cellular components in cells with high sensitivity and selectivity. Up to now, only indocyanine green (ICG) has been approved as a diagnostic reagent for intravenous application. But the intrinsic disadvantage of ICG has spurred more research attention to exploit new fluorescent materials in imaging fields. In the last decade, many materials, including inorganic and organic materials, have been developed for fluorescence imaging. There are some reviews about fluorescence bioimaging. In this review, we will summarize and highlight the reported organic nanoparticles for noninvasive long-term bioimaging. According to the emitting mechanism, fluorescent nanoparticles obtained from fluorophores with aggregation-caused quenching and aggregation-induced emission features are discussed respectively. Finally, we come up with some key issues and challenges in the future and clinical translation.

Graphical abstract: Robust organic nanoparticles for noninvasive long-term fluorescence imaging

Article information

Article type
Review Article
Submitted
04 Sep 2019
Accepted
11 Oct 2019
First published
18 Oct 2019

J. Mater. Chem. B, 2019,7, 6879-6889

Robust organic nanoparticles for noninvasive long-term fluorescence imaging

Y. Guan, T. Sun, J. Ding and Z. Xie, J. Mater. Chem. B, 2019, 7, 6879 DOI: 10.1039/C9TB01905G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements