Issue 5, 1997

Asymmetric synthesis of building-blocks for peptides and peptidomimetics by means of the β-lactam synthon method

Abstract

Recent advances in the syntheses of enantiopure synthetic building blocks useful for non-protein amino acids, dipeptides, oligopeptides using solid state peptide synthesis, isoserines (norstatines), dipeptide isosteres [hydroxy(keto)ethylene, hydroxyethylamine, hydroxyethylene and dihydroxyethylene isosteres], taxoids, polyamines, poly(amino alcohol)s and poly(amino ether)s, and other biologically active compounds through applications of the β-lactam Synthon method is reviewed.

Article information

Article type
Review Article

Chem. Soc. Rev., 1997,26, 377-386

Asymmetric synthesis of building-blocks for peptides and peptidomimetics by means of the β-lactam synthon method

I. Ojima and F. Delaloge, Chem. Soc. Rev., 1997, 26, 377 DOI: 10.1039/CS9972600377

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