A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H2S and its bioimaging applications in living cells and zebrafish

Hanchuang Zhu; Caiyun Liu; Changxu Liang; Bin Tian; Hanming Zhang; Xue Zhang; Wenlong Sheng; Yamin Yu; Shengyun Huang; Baocun Zhu

doi:10.1039/D0CC00282H

A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H₂S and its bioimaging applications in living cells and zebrafish†

Hanchuang Zhu,^a Caiyun Liu,

*^a Changxu Liang,^a Bin Tian,^b Hanming Zhang,^a Xue Zhang,^a Wenlong Sheng,*^b Yamin Yu,^a Shengyun Huang*^c and Baocun Zhu

*^a

Author affiliations

* Corresponding authors

^a School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China
E-mail: liucaiyun1982072@163.com, lcyzbc@163.com

^b Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China
E-mail: 15618694162@163.com

^c Department of Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China
E-mail: huangsy28@163.com

Abstract

We have synthesized a simple Golgi-targeting H₂S fluorescent probe which can detect endogenous and exogenous H₂S in cells and zebrafish. In addition, this probe provides a new chemical tool for the detailed study of generation pathways of H₂S under Golgi stress response.

Chemical Communications

A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H₂S and its bioimaging applications in living cells and zebrafish†

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A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H₂S and its bioimaging applications in living cells and zebrafish

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