Issue 34, 2020

Chirality sensing of terpenes, steroids, amino acids, peptides and drugs with acyclic cucurbit[n]urils and molecular tweezers

Abstract

Achiral chromophoric hosts, i.e. acyclic cucurbit[n]urils and molecular tweezers, were found to respond with characteristic Circular Dichroism (CD) spectra to the presence of micromolar concentrations of chiral hydrocarbons, terpenes, steroids, amino acids and their derivates, and drugs in water. In favourable cases, this allows for analyte identification or for reaction monitoring.

Graphical abstract: Chirality sensing of terpenes, steroids, amino acids, peptides and drugs with acyclic cucurbit[n]urils and molecular tweezers

Supplementary files

Article information

Article type
Communication
Submitted
27 Jan 2020
Accepted
24 Feb 2020
First published
25 Feb 2020
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 4652-4655

Chirality sensing of terpenes, steroids, amino acids, peptides and drugs with acyclic cucurbit[n]urils and molecular tweezers

A. Prabodh, D. Bauer, S. Kubik, P. Rebmann, F. G. Klärner, T. Schrader, L. Delarue Bizzini, M. Mayor and F. Biedermann, Chem. Commun., 2020, 56, 4652 DOI: 10.1039/D0CC00707B

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