Issue 60, 2020
From the journal:

Chemical Communications

Biotinylated platinum(ii) metallacage towards targeted cancer theranostics†

Xingchen Wang,a   Qi Su,b   Zeyuan Zhang, ORCID logo a   Jin Yang,c   Yanmin Zhang ORCID logo *b  and  Mingming Zhang ORCID logo *a  

* Corresponding authors

a State Key Laboratory for Mechanical Behavior of Materials, Shaanxi International Research Center for Soft Matter, School of Materials Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, P. R. China
E-mail: mingming.zhang@xjtu.edu.cn

b School of Pharmacy, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, P. R. China
E-mail: zhang2008@mail.xjtu.edu.cn

c Department of Medical Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, P. R. China

Abstract

A biotinylated metallacage was prepared via metal-coordination-driven self-assembly, combining fluorescence, anti-cancer and targeted properties into a single entity. The metallacage was successfully employed for targeted cell imaging and therapy, offering a platform for cancer theranostics.

Graphical abstract: Biotinylated platinum(ii) metallacage towards targeted cancer theranostics

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Article information

DOI
https://doi.org/10.1039/D0CC03824E
Article type
Communication
Submitted
30 May 2020
Accepted
18 Jun 2020
First published
18 Jun 2020

Chem. Commun., 2020,56, 8460-8463

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Biotinylated platinum(II) metallacage towards targeted cancer theranostics

X. Wang, Q. Su, Z. Zhang, J. Yang, Y. Zhang and M. Zhang, Chem. Commun., 2020, 56, 8460 DOI: 10.1039/D0CC03824E

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