Issue 72, 2021

A photosensitizer with conformational restriction for enhanced photodynamic therapy

Abstract

A rigid hemicyanine CSZ-J and a flexible molecule ESZ-J were synthesized. In particular, the conformationally restrained CSZ-J had higher fluorescence quantum yields, longer fluorescence lifetimes and higher triplet state quantum yields. CSZ-J could generate highly cytotoxic ROS simultaneously via type I and type II processes. This will contribute to the design and development of new photosensitizers in the future.

Graphical abstract: A photosensitizer with conformational restriction for enhanced photodynamic therapy

Supplementary files

Article information

Article type
Communication
Submitted
05 Jul 2021
Accepted
10 Aug 2021
First published
10 Aug 2021

Chem. Commun., 2021,57, 9100-9103

A photosensitizer with conformational restriction for enhanced photodynamic therapy

H. Huang, S. Long, D. Huang, J. Du, J. Fan and X. Peng, Chem. Commun., 2021, 57, 9100 DOI: 10.1039/D1CC03591F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements