Characterization of polyatomic ion interferences in inductively coupled plasma mass spectrometry using a high resolution mass spectrometer

Abstract

The effect of common interferences on the ICP-MS of the elements from Li through to Ge has been catalogued. The study utilizes the resolving power available from a double focusing mass spectrometer and provides definitive information regarding the nature and potential origin of such species. The study investigates several common anion matrices typical of the normal acids used in practical analysis (sulfate, nitrate and chloride) as well as the concomitants present from atomospheric entrainment into the argon plasma (C, N, H and O). The resulting database should provide a useful reference guide as to which interferences need to be considered in any practical analysis, whether using a quadrupole or a sector-based instrument.