Conversion of alcohols into alkyl bromides using polymer-supported triphenylphosphine dibromide and polymer-supported triphenylphosphine and carbon tetrabromide

Abstract

Alcohols were converted into alkyl bromides by reaction with polymer-supported triphenylphosphine dibromide and with polymer-supported triphenylphosphine and carbon tetrabromide. With both reagents excellent yields of bromides were obtained, but the reactions with the latter reagent were faster and cleaner and in favourable cases high yields of bromide were obtained within 15 min at 20 °C. An advantage of the polymer-supported reagents is that product isolation is facilitated by the ready separation of the supported from the non-supported species.