Synthesis of the yeast antioxidant benzofuran and analogues
Abstract
2-(6-Hydroxy-2-methoxy-3,4-methylenedioxyphenyl)benzofuran, the active antioxidant which occurs in yeasts, and related 2-arylbenzofurans have been synthesized by a convergent route. The key step involves benzofuran formation by an intramolecular Wittig reaction.