Issue 0, 1985

5,6,7,8-Tetrahydroquinolines. Part 7. Synthesis of 8-cyano-5,6,7,8-tetrahydroquinolines; di-isopropylcyanamide, a new reagent for cyanation of organometallics

Abstract

Di-isopropylcyanamide (1) is an effective reagent for the conversion of 8-lithio-5,6,7,8-tetra-hydroquinolines into 8-cyano-5,6,7,8-tetrahydroquinolines. 8,8-Dicyano derivatives are not formed. A convenient synthesis of the reagent from disodium cyanamide is described.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1985, 2479-2481

5,6,7,8-Tetrahydroquinolines. Part 7. Synthesis of 8-cyano-5,6,7,8-tetrahydroquinolines; di-isopropylcyanamide, a new reagent for cyanation of organometallics

R. Crossley and R. G. Shepherd, J. Chem. Soc., Perkin Trans. 1, 1985, 2479 DOI: 10.1039/P19850002479

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