Issue 1, 1989

Possible effect of hydrogen bonding on methylation of pyrimidine and pyridone nucleosides

Abstract

Methylation of 1-(β-D-ribofuranosyl)-2-pyridone and -4-pyridone and 3-methyluridine with trimethylsulphonium hydroxide suggested that pyrimidine ribonucleosides (cytidine and uridine) differed in reactivity from the corresponding deoxyribonucleosides because of hydrogen bonding between the 2′-OH and C(2)[double bond, length half m-dash]O groups.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1989, 13-15

Possible effect of hydrogen bonding on methylation of pyrimidine and pyridone nucleosides

K. Yamauchi, T. Hosokawa and M. Kinoshita, J. Chem. Soc., Perkin Trans. 1, 1989, 13 DOI: 10.1039/P19890000013

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