Issue 5, 1989

Model studies directed toward the total synthesis of 14-membered cyclopeptide alkaloids: synthesis of prolyl peptides via a four-component condensation

Abstract

The general applicability of a four-component condensation for the formation of N-acyl-β-aryloxyprolines has been demonstrated in several model studies. The relative stereochemistry of the diastereoisomers obtained has been assigned from 1H n.m.r. studies, and confirmed by an X-ray analysis of one of the stereoisomers.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1989, 857-865

Model studies directed toward the total synthesis of 14-membered cyclopeptide alkaloids: synthesis of prolyl peptides via a four-component condensation

M. M. Bowers, P. Carroll and M. M. Joullié, J. Chem. Soc., Perkin Trans. 1, 1989, 857 DOI: 10.1039/P19890000857

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