SCHEDULED MAINTENANCE
The reaction of diethylzinc with a range of arenecarbaldehydes has been catalysed by N-alkyl ephedrines to give 1-arylpropan-1-ols with good to excellent optical yields. The enantioselectivity of the reaction was substantially improved by the use of a 4 molar excess of the organozinc reagent.
P. A. Chaloner, E. Langadianou and S. A. R. Perera, J. Chem. Soc., Perkin Trans. 1, 1991, 2731 DOI: 10.1039/P19910002731
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