Issue 14, 1994

Studies on Rubia akane(RA) derivatives. Part 7. Thioamide analogues of RAs: antitumour cyclic hexapeptides

Abstract

[Tyr-3-ψ(CS-NH)-Ala-4]RA-VII 3, [Tyr-3-ψ(CS-NH)-Ala-4; Tyr-6-ψ(CS-NH)-D-Ala-1]RA-VII 4, [Tyr-3-ψ(CS-NH)-Ala-4]RA-V 7 and [Tyr-3-ψ(CS-NH)-Ala-4]RA-X methyl ester 8 have been prepared from corresponding RAs, and they showed more promising in vitro antitumour activity than the parent compounds.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1994, 1887-1889

Studies on Rubia akane(RA) derivatives. Part 7. Thioamide analogues of RAs: antitumour cyclic hexapeptides

Y. Hitotsuyanagi, J. Suzuki, Y. Matsumoto, K. Takeya and H. Itokawa, J. Chem. Soc., Perkin Trans. 1, 1994, 1887 DOI: 10.1039/P19940001887

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