Issue 7, 1995

A new and convenient one-pot synthesis of α,β-unsaturated trifluoromethyl ketones

Abstract

Alkylphosphonates react with N-phenyltrifluoroacetimidoyl chloride in the presence of lithium diisopropylamide to afford mixtures which when treated with aldehydes and subjected to acid hydrolysis afford α,β-unsaturated trifluoromethyl ketones.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1995, 741-742

A new and convenient one-pot synthesis of α,β-unsaturated trifluoromethyl ketones

W. S. Huang and C. Y. Yuan, J. Chem. Soc., Perkin Trans. 1, 1995, 741 DOI: 10.1039/P19950000741

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