SCHEDULED MAINTENANCE
The newly synthesised Pβ,–Pγ-difluoromethylenebisphosphonate analogue 2 of nor-carbovir triphosphate is a potent inhibitor of HIV reverse transcriptase; it also exhibits a greatly enhanced stability to dephosphorylation, in foetal blood serum, relative to AZTTP and other nucleoside triphosphates.
C. J. Hamilton, S. M. Roberts and A. Shipitsin, Chem. Commun., 1998, 1087 DOI: 10.1039/A801127C
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