Issue 2, 2001
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

The chemistry of lithiated phosphine oxides: the stereoselective synthesis of alkene-4,5-diols

Thomas Boesen,a   Neil Feeder,a   Martin D. Eastgate,a   David J. Fox,a   Jonathan A. Medlock,a   Charles R. Tyzacka  and  Stuart Warren*a  

* Corresponding authors

a University Chemistry Laboratory, Lensfield Road, Cambridge, UK

Abstract

Single enantiomers of (E )-1,5-diarylpentene-4,5-diols have been synthesised by Horner–Wittig elimination. The stereochemistry is controlled by an asymmetric dihydroxylation, and a stereoselective reduction of a β-keto phosphine oxide.

Graphical abstract: The chemistry of lithiated phosphine oxides: the stereoselective synthesis of alkene-4,5-diols

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B008500F
Article type
Paper
Submitted
20 Oct 2000
Accepted
27 Oct 2000
First published
14 Dec 2000

J. Chem. Soc., Perkin Trans. 1, 2001, 118-126

Permissions

Request permissions

The chemistry of lithiated phosphine oxides: the stereoselective synthesis of alkene-4,5-diols

T. Boesen, N. Feeder, M. D. Eastgate, D. J. Fox, J. A. Medlock, C. R. Tyzack and S. Warren, J. Chem. Soc., Perkin Trans. 1, 2001, 118 DOI: 10.1039/B008500F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements