Issue 11, 2003

Non-covalent stabilization of a β-hairpin peptide into liposomes

Abstract

An oligopeptide modified on both the N- and C-termini with hydrophobic moieties was prepared on a solid phase and anchored into a liposome, stabilizing the fold of the peptide into a β-hairpin, which would otherwise be a random coil.

Graphical abstract: Non-covalent stabilization of a β-hairpin peptide into liposomes

Article information

Article type
Communication
Submitted
04 Apr 2003
Accepted
07 May 2003
First published
12 May 2003

Org. Biomol. Chem., 2003,1, 1827-1829

Non-covalent stabilization of a β-hairpin peptide into liposomes

D. W. P. M. Löwik, J. G. Linhardt, P. J. H. M. Adams and J. C. M. V. Hest, Org. Biomol. Chem., 2003, 1, 1827 DOI: 10.1039/B303749E

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