Issue 5, 2008

A primer on ankyrin repeat function in TRP channels and beyond

Abstract

Transient receptor potential (TRP) channels are rapidly gaining attention as important receptors and transducers of diverse sensory and environmental cues. Recent progress in the field has provided new insights into the structure and function of the ankyrin repeat motifs present in the N-terminal cytosolic domain of many TRP channels. The topics addressed in this Highlight include the structural features of canonical ankyrin repeats, new clues into the functions these repeats perform in cells, and how this information can be applied to develop further experiments on TRP channels and other proteins containing ankyrin repeats.

Graphical abstract: A primer on ankyrin repeat function in TRP channels and beyond

Article information

Article type
Highlight
First published
26 Mar 2008

Mol. BioSyst., 2008,4, 372-379

A primer on ankyrin repeat function in TRP channels and beyond

R. Gaudet, Mol. BioSyst., 2008, 4, 372 DOI: 10.1039/B801481G

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