Issue 39, 2008

Specific interactions between silver(i) ions and cytosine–cytosine pairs in DNA duplexes

Abstract

Very specific binding of the Ag(I) ion unexpectedly stabilized DNA duplexes containing the naturally occurring cytosinecytosine (C–C) mismatch-base pair; because the C–C pair selectively binds to the Ag(I) ion, we developed a DNA-based Ag(I) sensor that employed an oligodeoxyribonucleotide containing C–C pairs used for Ag(I) binding sites.

Graphical abstract: Specific interactions between silver(i) ions and cytosine–cytosine pairs in DNA duplexes

Supplementary files

Article information

Article type
Communication
Submitted
22 May 2008
Accepted
08 Jul 2008
First published
22 Aug 2008

Chem. Commun., 2008, 4825-4827

Specific interactions between silver(I) ions and cytosinecytosine pairs in DNA duplexes

A. Ono, S. Cao, H. Togashi, M. Tashiro, T. Fujimoto, T. Machinami, S. Oda, Y. Miyake, I. Okamoto and Y. Tanaka, Chem. Commun., 2008, 4825 DOI: 10.1039/B808686A

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